Cast Overview

Faculty

 * Debbie Allen as Lydia Grant
 * Albert Hague as Benjamin Shorofsky
 * Carol Mayo Jenkins as Elizabeth Sherwood (seasons 1-5)
 * Ann M. Nelson as Mrs. Gertrude Berg (Seasons 1-6)
 * Ken Swofford as Quentin Morloch (Seasons 3- 5.09)
 * Graham Jarvis as Principal Bob Dyrenforth (Seasons 5.10- 6)
 * Morgan Stevens as David Reardon (season 2, recurring seasons 3 & 4)
 * Eric Pierpoint as Paul Seeger (Season 6.03)
 * Michael Thoma as Greg Crandall (Season 1)

Students

 * Gene Anthony Ray as Leroy Johnson
 * Carlo Imperato as Danny Amatullo (Seasons 1-6)Carlo_Imperato_2.jpg
 * Billy Hufsey as Christopher Donlon (seasons 3-6)
 * Valerie Landsburg-McVay as Doris Schwartz (seasons 1-4)
 * Jesse Borrego as Jesse Velasquez (seasons 4-6)
 * Lee Curreri as Bruno Martelli (seasons 1-3)
 * Cynthia Gibb as Holly Laird (seasons 3-5)
 * Nia Peeples George as Nicole Chapman (seasons 4-6)
 * Erica Gimpel as Coco Hernandez (seasons 1-3,recurring Seasons 4-6)
 * Loretta Chandler as Dusty Tyler (seasons 5-6)
 * Lori Singer as Julie Miller (seasons 1-2)
 * Carrie Hamilton as Reggie Higgins (seasons 5-6)
 * Janet Jackson as Cleo Hewitt (season 4)
 * Michael Cerveris as Ian Ware (season 6)
 * Elisa Heinsohn as Jillian Beckett (season 6)
 * P.R. Paul as Montgomery MacNeil (season 1, final episode of season 6)
 * Page Hannah as Kate Riley (seasons 5)
 * Olivia Barash as Maxie Sharp (season 6)

Additional characters

 * Dick Miller as Lou Mackie (season 6, recurring previously on seasons 4 & 5)
 * Stephanie E. Williams as Stephanie Harrison (season 2)

Recurring characters

 * Carmine Caridi as Angelo Martelli (seasons 1–2)
 * Michael DeLorenzo as Michael (seasons 1–3)
 * Denny Dillon as Corky (season 6)
 * David Greenlee as Dwight Mendenhall (seasons 2–5)
 * Robert Romanus as Miltie Horowitz (seasons 5–6)
 * Carolyn J. Silas as Laura Mackie (season 6)
 * Sam Slovick as Cassidy (season 4)
 * Bronwyn Thomas as Michelle (season 1–4)
 * Caryn Ward as Tina Johnson (seasons 5–6)